Magnetic Resonance Imaging Lab Research groups

The Magnetic Resonance Imaging (MRI) Laboratory makes use of nanomaterials and magnetic resonance imaging techniques on animal models. On one hand, we intend to characterize the onset and evolution of diseases of the Central Nervous System (from development of early markers to imaging methods that quantify the progression of the pathological processes and their consequences at anatomical and functional levels). We additionally develop new therapeutic approaches to treat such diseases, with special emphasis on the penetration through the blood-brain-barrier, and monitoring the effective release of drugs in the brain parenchyma. The main research lines are described below.

 Main Research Lines: 

Imaging of demyelination-remyelination processes  
a. Multi-parametric high resolution imaging of white matter
b. In vitro and in vivo quantification of myelin 
c. Nanomaterials for theranostics on demyelination processes

 Functional imaging of the CNS
a. Functional imaging on animal models of disease
b. Integration of fMRI with DTI and fiber tracking techniques
c. Optogenetics and genetic sensors of neuronal activity

 Imaging drug delivery
a. Imaging sensors of nanodrugs integrity for imaging delivery
b. Responsive nanosystems for activatable drug delivery 
c. Enhancement and visualization of the crossing of the blod-brain-barrier (BBB)

Science field

Life & Medical Sciences

RIS3 Priorities
  • Biosciences & Health
Main researcher
Pedro Ramos
CIC biomaGUNE Parque tecnológico de Gipuzkoa Ed. Pº Miramón 182, 20014, San Sebastián
How to arrive
Main research lines
  • Imaging of demyelination-remyelination processes
  • Functional imaging of the CNS
  • Imaging drug delivery